中国针灸

目的：观察针刺对血虚风燥型慢性湿疹（CE）患者临床症状、中医证候及生活质量的影响。方法：将48例血虚风燥型CE患者随机分为观察组（24例，脱落1例）和对照组（24例，脱落2例）。两组在基础皮肤护理以外，观察组予针刺治疗，主穴取双侧申脉、后溪、阴陵泉、曲池、蠡沟、三阴交、血海，并随症配穴，每次留针20 min，前2周每周3次，后2周每周2次；对照组予糠酸莫米松乳膏外涂治疗，前2周每日1次，后2周每周2次。两组均治疗4周。观察两组治疗前后湿疹面积及严重程度指数（EASI）评分、瘙痒视觉模拟量表（VAS）评分、中医证候评分、皮肤病生活质量量表（DLQI）评分；检测两组血清免疫球蛋白E(Ig E)水平；观察两组治疗后疗效及治疗结束后4周随访时复发率。结果：治疗后，两组患者EASI评分、瘙痒VAS评分、DLQI评分、血清Ig E水平及观察组中医证候评分均较治疗前降低（P<0.01），观察组以上指标均低于对照组（P<0.01,P<0.05）。观察组总有效率为91.3%(21/23)，高于对照组的63.6%(14/22,P<0.05)；随访时两组复发率比较，差异无统计学意义（P>0.05）。结论：针刺可以改善血虚风燥型CE患者临床症状、中医证候，提高生活质量。

Objective To observe the effects of acupuncture on the clinical efficacy, TCM syndromes and quality of life of patients with chronic eczema(CE) of blood deficiency stirring wind. Methods Forty-eight patients of CE with blood deficiency stirring wind were randomly divided into an observation group(24 cases, 1 case dropped out) and a control group(24 cases, 2 cases dropped out). Both groups received basic skin care. The observation group received acupuncture at bilateral Shenmai(BL62), Houxi(SI3), Yinlingquan(SP9), Quchi(LI11), Ligou(LR5), Sanyinjiao(SP6), Xuehai(SP10), additional acupoints were supplemented based on symptom differentiation, 20 min each time, 3 times a week for the first 2 weeks, 2 times a week for the subsequent 2 weeks. The control group was treated with mometasone furoate cream, once a day for the first 2 weeks, twice a week for the subsequent 2 weeks. Both groups were treated for 4 weeks. The scores of eczema area and severity index(EASI), itch visual analogue scale(VAS), TCM syndrome, dermatology life quality index(DLQI) of the two groups were observed before and after treatment, the serum level of immunoglobulin E(IgE) was detected, and the clinical efficacy after treatment and follow-up recurrence rate after 4 weeks of treatment completion of the two groups were observed. Results After treatment, the scores of EASI, itch VAS, DLQI and serum levels of IgE in both groups and the score of TCM syndrome in the observation group were decreased compared with those before treatment(P<0.01);the above indexes in the observation group were lower than those in the control group(P<0.01, P<0.05). The total effective rate of the observation group was 91.3%(21/23), which was higher than 63.6%(14/22) in the control group(P<0.05). In follow-up, the difference in recurrence rates between the two groups was not statistically significant(P>0.05). Conclusion Acupuncture can improve the clinical symptoms, TCM syndrome, quality of life of CE patients with blood deficiency stirring wind.