中国针灸

参考文献

[1]李舜伟.认知功能障碍的诊断与治疗[J].中国神经精神疾病杂志，2006，32(2):189-191.

[2] Pennington C， Newson M， Hayre A， et al. Functional cognitive disorder: what is it and what to do about it?[J]. Pract Neurol， 2015， 15(6): 436-444.

[3] World Health Organization.Global action plan on the public health response to dementia 2017-2025[EB/OL].[2025-08-14].https://www.who.int/publications/i/item/9789241513487.

[4]赵天赐， 郭少博， 赵璧卿， 等. 轻度认知障碍的流行病学研究进展[J]. 中医研究， 2025，38(2):92-96.

[5] Hao LX， Wang XN， Zhang L， et al. Prevalence， risk factors， and complaints screening tool exploration of subjective cognitive decline in a large cohort of the Chinese population[J]. J Alzheimers Dis， 2017， 60(2): 371-388.

[6] Sanford AM. Mild cognitive impairment[J]. Clin Geriatr Med， 2017， 33(3): 325-337.

[7] Hill NT， Mowszowski L， Naismith SL， et al. Computerized cognitive training in older adults with mild cognitive impairment or dementia: a systematic review and meta-analysis[J]. Am J Psychiatry， 2017， 174(4): 329-340.

[8]李娜， 梁炜东， 张善红， 等. 老年人轻度认知障碍非药物干预研究进展[J]. 中国护理管理， 2018，18(5):688-692.

[9]Petersen RC， Lopez O， Armstrong MJ， et al. Practice guideline update summary: Mild cognitive impairment[RETIRED]: Report of the Guideline Development， Dissemination， and Implementation Subcommittee of the American Academy of Neurology[J]. Neurology，2018， 90(3): 126-135.

[10] 曹燕， 赵吉平， 汪露， 等. 针刺改善非痴呆型血管性认知障碍患者相关认知域：一项多中心随机对照研究的二次分析[J]. 中华中医药杂志， 2024，39(12): 6878-6881.

[11] Lee S， Hahn C， Seong E， et al. Reactive EEG biomarkers for diagnosis and prognosis of Alzheimer’s disease and mild cognitive impairment[J]. Biosens Bioelectron， 2025， 273: 117181.

[12] Perez V， Garrido-Chaves R， Zapater-Fajarí M， et al. EEG markers and subjective memory complaints in young and older people[J]. Int J Psychophysiol， 2022， 182: 23-31.

[13] Wang Y， Ye X， Song B， et al. Features of event-related potentials during retrieval of episodic memory in patients with mild cognitive impairment due to Alzheimer’s disease[J]. Front Neurosci， 2023， 17: 1185228.

[14] Zheng XY， Lin WJ， Jiang YM， et al. Electroacupuncture ameliorates beta-amyloid pathology and cognitive impairment in Alzheimer disease via a novel mechanism involving activation of TFEB (transcription factor EB)[J]. Autophagy， 2021， 17(11): 3833-3847.

[15] Chen HT， Yang XK， Gao YS， et al. Electroacupuncture ameliorates cognitive impairment in APP/PS1 mouse by modulating TFEB levels to relieve ALP dysfunction[J]. Brain Res， 2024， 1823: 148683.

[16] Cai MD， Lee JH， Yang EJ. Electroacupuncture attenuates cognition impairment via anti-neuroinflammation in an Alzheimer's disease animal model[J]. J Neuroinflammation， 2019， 16(1): 264.

[17] 王渊， 刘智斌， 牛文民， 等. “嗅三针”对阿尔茨海默病小鼠空间记忆能力和海马APP、Aβ蛋白表达的影响[J]. 陕西中医， 2018，39(2):139-142.

[18] Su X， Wu ZQ， Mai FY， et al. ‘Governor vessel-unblocking and mind-regulating’ acupuncture therapy ameliorates cognitive dysfunction in a rat model of middle cerebral artery occlusion[J]. Int J Mol Med， 2019， 43(1): 221-232.

[19] 吕转， 陈玉龙， 王亚敏， 等. 通督醒神电针调节代谢通路改善脑缺血再灌注大鼠学习记忆障碍[J]. 中国中西医结合杂志， 2025，45(6):692-698.

[20] Xu AP， Tang YS， Zeng QT， et al. Electroacupuncture enhances cognition by promoting brain glucose metabolism and inhibiting inflammation in the APP/PS1 mouse model of Alzheimer’s disease: a pilot study[J]. J Alzheimers Dis， 2020， 77(1): 387-400.

[21] Ding N， Jiang J， Xu AP， et al. Manual acupuncture regulates behavior and cerebral blood flow in the SAMP8 mouse model of Alzheimer’s disease[J]. Front Neurosci， 2019， 13: 37.

[22] Ma SM， Wang L， Su XT， et al. Acupuncture improves white matter perfusion and integrity in rat model of vascular dementia: an MRI-based imaging study[J]. Front Aging Neurosci， 2020， 12: 582904.

[23] Chen ZH， Wang XR， Du SM， et al. A review on traditional Chinese medicine natural products and acupuncture intervention for Alzheimer’s disease based on the neuroinflammatory[J]. Chin Med， 2024， 19(1): 35.

[24] 赵耀， 梅书雅， 雷露， 等. 针灸改善阿尔茨海默病突触可塑性机制研究进展[J]. 针灸临床杂志， 2024，40(4):100-104.

[25] Ji SZ， Duan JY， Hou XB， et al. The role of acupuncture improving cognitive deficits due to Alzheimer’s disease or vascular diseases through regulating neuroplasticity[J]. Neural Plast， 2021， 2021: 8868447.

[26] Jiang P， Hu F， Lin M， et al. Clinical efficacy of acupuncture on mild cognitive impairment and its effect on gut microbiota[J]. Zhong guo Zhen Jiu， 2025，45(7): 903-910.

[27] Ba T， Niu R， Gao JJ， et al. Microbiota-gut-brain-axis: a new target of acupuncture therapy for post-stroke cognitive impairment[J]. Front Microbiol， 2025， 16: 1425054.

[28] Ma SQ， Huang HP， Zhong Z， et al. Effect of acupuncture on brain regions modulation of mild cognitive impairment: a meta-analysis of functional magnetic resonance imaging studies[J]. Front Aging Neurosci， 2022， 14: 914049.

[29] Han YM， Li YJ， Zhang H， et al. Exploring the changes in functional connectivity of the limbic system in Patients with amnestic mild cognitive impairment treated by acupuncture based on fMRI[J]. Front Neurol， 2025， 16: 1506367.

[30] 韩盛旺， 李晓陵， 王杨， 等. 针刺四关穴治疗轻度认知障碍多模态MRI研究进展[J]. 磁共振成像， 2024，15(6):138-143.

[31] Lopes da Silva F. EEG and MEG: relevance to neuroscience[J]. Neuron， 2013， 80(5): 1112-1128.

[32] Lejko N， Larabi DI， Herrmann CS， et al. Alpha power and functional connectivity in cognitive decline: a systematic review and meta-analysis[J]. J Alzheimers Dis， 2020， 78(3): 1047-1088.

[33] Musaeus CS， Engedal K， H?gh P， et al. EEG Theta Power is an early marker of cognitive decline in dementia due to Alzheimer’s disease[J]. J Alzheimers Dis， 2018， 64(4): 1359-1371.

[34] Jeong HT， Youn YC， Sung HH， et al. Power spectral changes of quantitative EEG in the subjective cognitive decline: comparison of community normal control groups[J]. Neuropsychiatr Dis Treat， 2021， 17: 2783-2790.

[35] Azami H， Zrenner C， Brooks H， et al. Beta to Theta power ratio in EEG periodic components as a potential biomarker in mild cognitive impairment and Alzheimer’s dementia[J]. Alzheimers Res Ther， 2023， 15(1): 133.

[36] Moretti DV， Paternicò D， Binetti G， et al. EEG upper/low alpha frequency power ratio and the impulsive disorders network in subjects with mild cognitive impairment[J]. Curr Alzheimer Res， 2014， 11(2): 192-199.

[37] Moretti DV， Pievani M， Pini L， et al. Cerebral PET glucose hypometabolism in subjects with mild cognitive impairment and higher EEG high-alpha/low-alpha frequency power ratio[J]. Neurobiol Aging， 2017， 58: 213-224.

[38] 陈玉宝. 针刺对血管性痴呆患者定量脑电图的影响[J]. 现代中西医结合杂志， 2012，21(30):3368-3369.

[39] 赵东雪. 不同频率电针刺激情感区改善卒中后认知障碍执行功能及对定量脑电图影响的临床研究[D]. 哈尔滨:黑龙江中医药大学， 2024.

[40] Yu HT， Wu XY， Cai LH， et al. Modulation of spectral power and functional connectivity in human brain by acupuncture stimulation[J]. IEEE Trans Neural Syst Rehabil Eng， 2018， 26(5): 977-986.

[41] Yu HT， Li F， Liu JL， et al. Evaluation of acupuncture efficacy in modulating brain activity with periodic-aperiodic EEG measurements[J]. IEEE Trans Neural Syst Rehabil Eng， 2024， 32: 2450-2459.

[42] Lehmann D， Strik WK， Henggeler B， et al. Brain electric microstates and momentary conscious mind states as building blocks of spontaneous thinking: I. Visual imagery and abstract thoughts[J]. Int J Psychophysiol， 1998， 29(1): 1-11.

[43] Britz J， Van De Ville D， Michel CM. BOLD correlates of EEG topography reveal rapid resting-state network dynamics[J]. Neuroimage， 2010， 52(4): 1162-1170.

[44] Milz P， Faber PL， Lehmann D， et al. The functional significance of EEG microstates: Associations with modalities of thinking[J]. Neuroimage， 2016， 125: 643-656.

[45] Pedroni A， Gianotti LRR， Koenig T， et al. Temporal characteristics of EEG microstates mediate trial-by-trial risk taking[J]. Brain Topogr， 2017， 30(1): 149-159.

[46] Santarnecchi E， Khanna AR， Musaeus CS， et al. EEG microstate correlates of fluid intelligence and response to cognitive training[J]. Brain Topogr， 2017， 30(4): 502-520.

[47] Tarailis P， Koenig T， Michel CM， et al. The functional aspects of resting EEG microstates: a systematic review[J]. Brain Topogr， 2024， 37(2): 181-217.

[48] Lassi M， Fabbiani C， Mazzeo S， et al. Degradation of EEG microstates patterns in subjective cognitive decline and mild cognitive impairment: Early biomarkers along the Alzheimer’s Disease continuum?[J]. Neuroimage Clin， 2023， 38: 103407.

[49] Perez V， Duque A， Hidalgo V， et al. EEG frequency bands in subjective cognitive decline: a systematic review of resting state studies[J]. Biol Psychol， 2024， 191: 108823.

[50] Gouw AA， Alsema AM， Tijms BM， et al. EEG spectral analysis as a putative early prognostic biomarker in nondemented， amyloid positive subjects[J]. Neurobiol Aging， 2017， 57: 133-142.

[51] Lian HP， Li YJ， Li YX. Altered EEG microstate dynamics in mild cognitive impairment and Alzheimer’s disease[J]. Clin Neurophysiol， 2021， 132(11): 2861-2869.

[52] Musaeus CS， Engedal K， H?gh P， et al. Changes in the left temporal microstate are a sign of cognitive decline in patients with Alzheimer’s disease[J]. Brain Behav， 2020， 10(6): e01630.

[53] Zhang K， Shen JH， Liu TY， et al. Modulation of brain activities in healthy individuals by acupuncture at Quchi (LI11)[J]. Brain Topogr， 2024， 38(1): 5.

[54] Si XP， Han SL， Zhang K， et al. The temporal dynamics of EEG microstate reveals the neuromodulation effect of acupuncture with Deqi[J]. Front Neurosci， 2021， 15: 715512.

[55] 刘琳. 针刺太冲穴与丘墟穴的大脑时空动态效应研究[D]. 泸州:西南医科大学， 2020.

[56] Lazarou I， Nikolopoulos S， Dimitriadis SI， et al. Is brain connectome research the future frontier for subjective cognitive decline? A systematic review[J]. Clin Neurophysiol， 2019， 130(10): 1762-1780.

[57] Smailovic U， Koenig T， Savitcheva I， et al. Regional disconnection in Alzheimer dementia and amyloid-positive mild cognitive impairment: association between EEG functional connectivity and brain glucose metabolism[J]. Brain Connect， 2020， 10(10): 555-565.

[58] Kim SE， Shin C， Yim J， et al. Resting-state electroencephalographic characteristics related to mild cognitive impairments[J]. Front Psychiatry， 2023， 14: 1231861.

[59] Chetty CA， Bhardwaj H， Kumar GP， et al. EEG biomarkers in Alzheimer’s and prodromal Alzheimer’s: a comprehensive analysis of spectral and connectivity features[J]. Alzheimers Res Ther， 2024， 16(1): 236.

[60] Zheng H， Xiao H， Zhang YN， et al. Time-Frequency functional connectivity alterations in Alzheimer’s disease and frontotemporal dementia: an EEG analysis using machine learning[J]. Clin Neurophysiol， 2025， 170: 110-119.

[61] Jiang Y， Zhang X， Guo ZW， et al. Altered EEG Theta and alpha band functional connectivity in mild cognitive impairment during working memory coding[J]. IEEE Trans Neural Syst Rehabil Eng， 2024， 32: 2845-2853.

[62] Duan F， Huang ZH， Sun Z， et al. Topological network analysis of early Alzheimer’s disease based on resting-state EEG[J]. IEEE Trans Neural Syst Rehabil Eng， 2020， 28(10): 2164-2172.

[63] Jiang Y， Guo ZW， Zhou XB， et al. Exploration of working memory retrieval stage for mild cognitive impairment: time-varying causality analysis of electroencephalogram based on dynamic brain networks[J]. J Neuroeng Rehabil， 2025， 22(1): 58.

[64] Yin ZH， Zhou J， Xia MZ， et al. Acupuncture on mild cognitive impairment: A systematic review of neuroimaging studies[J]. Front Aging Neurosci， 2023， 15: 1007436.

[65] Wang X， Zhou H， Yan CQ， et al. Cognitive and hippocampal changes in older adults with subjective cognitive decline after acupuncture intervention[J]. Am J Geriatr Psychiatry， 2024， 32(8): 1014-1027.

[66] Tan TT， Wang D， Huang JK， et al. Modulatory effects of acupuncture on brain networks in mild cognitive impairment patients[J]. Neural Regen Res， 2017， 12(2): 250-258.

[67] Cera N， Esposito R， Cieri F， et al. Altered cingulate cortex functional connectivity in normal aging and mild cognitive impairment[J]. Front Neurosci， 2019， 13: 857.

[68] Jeong HJ， Lee YM， Park JM， et al. Reduced thickness of the anterior cingulate cortex as a predictor of amnestic-mild cognitive impairment conversion to Alzheimer’s disease with psychosis[J]. J Alzheimers Dis， 2021， 84(4): 1709-1717.

[69] Deng DM， Liao H， Duan GX， et al. Modulation of the default mode network in first-episode， drug-Na?ve major depressive disorder via acupuncture at Baihui (GV20) acupoint[J]. Front Hum Neurosci， 2016， 10: 230.

[70] Wang YY， Liu Z， Chen F， et al. Effects of acupuncture on craving after tobacco cessation: a resting-state fMRI study based on the fractional amplitude of low-frequency fluctuation[J]. Quant Imaging Med Surg， 2019， 9(6): 1118-1125.

[71] Yin ZH， Wang ZQ， Li YQ， et al. Neuroimaging studies of acupuncture on Alzheimer’s disease: a systematic review[J]. BMC Complement Med Ther， 2023， 23(1): 63.

[72] Meghdadi AH， Salat D， Hamilton J， et al. EEG and ERP biosignatures of mild cognitive impairment for longitudinal monitoring of early cognitive decline in Alzheimer’s disease[J]. PLoS One， 2024， 19(8): e0308137.

[73] Paitel ER， Samii MR， Nielson KA. A systematic review of cognitive event-related potentials in mild cognitive impairment and Alzheimer’s disease[J]. Behav Brain Res， 2021， 396: 112904.

[74] Ieracitano C， Mammone N， Hussain A， et al. A novel multi-modal machine learning based approach for automatic classification of EEG recordings in dementia[J]. Neural Netw， 2020， 123: 176-190.

[75] 吴林纳， 李凯， 宋蕊好， 等. 基于脑电图技术探讨曲池针刺作用下的脑网络神经动态特征[J]. 中国中医药信息杂志， 2023，30(12):153-158.

[76] Rao WH， Xu MY， Wang HC， et al. Acupuncture state detection at Zusanli (ST-36) based on scalp EEG and transformer[J]. IEEE J Biomed Health Inform， 2025， 29(6): 4023-4034.