564 | 0 | 226 |
下载次数 | 被引频次 | 阅读次数 |
目的:观察热敏灸联合西药治疗阳气亏虚型老年体位性低血压(OH)的临床疗效。方法:将60例阳气亏虚型老年OH患者随机分为观察组(30例,脱落1例)和对照组(30例)。对照组予盐酸米多君片口服,每次2.5 mg,每天2次;观察组在对照组基础上行热敏灸治疗,穴取大椎、风府、百会,每次30~40 min,每天1次。两组均治疗4周。分别于治疗前及治疗2、4周后观察两组患者卧位及立位血压、卧位转立位时血压下降值,并评定临床疗效。结果:治疗4周后,两组患者卧位及立位收缩压(SBP)、舒张压(DBP)均较治疗前升高(P<0.05),卧位转立位时SBP、DBP下降值均较治疗前降低(P<0.05);观察组卧位及立位SBP、DBP高于对照组(P<0.05),卧位转立位时SBP、DBP下降值低于对照组(P<0.05)。观察组总有效率为96.6%(28/29),高于对照组的70.0%(21/30,P<0.05)。结论:热敏灸联合西药可升高阳气亏虚型老年OH患者的卧位及立位血压,降低卧位转立位血压下降值。
Abstract:Objective To observe the effect of heat-sensitive moxibustion combined with medication on orthostatic hypotension(OH) of yang-qi deficiency in the elderly. Methods Sixty elderly patients with OH of yang-qi deficiency were randomly divided into an observation group(30 cases, 1 case dropped out) and a control group(30 cases). The patients in the control group were treated with oral midodrine hydrochloride tablets, 2.5 mg each time and twice daily, while the patients in the observation group were treated with heat-sensitive moxibustion in addition to the treatment in the control group.Acupoints selected included Dazhui(GV 14), Fengfu(GV 16), and Baihui(GV 20), with each session lasting 30-40 min, once daily. Both groups were treated for 4 weeks. Blood pressure in the supine and standing positions, as well as the decrease of blood pressure when the position changing from supine to standing, were measured before treatment and after 2 and 4 weeks of treatment. Clinical efficacy was also evaluated. Results After 4 weeks of treatment, both groups showed an increase in systolic blood pressure(SBP) and diastolic blood pressure(DBP) in both the supine and standing positions(P<0.05), and the decrease in SBP and DBP when the position changing from supine to standing was reduced(P<0.05). Compared with the control group, the observation group had higher SBP and DBP in both positions and a smaller decrease in SBP and DBP when the position changing from supine to standing(P<0.05). The total effective rate was 96.6%(28/29) in the observation group,which was higher than 70.0%(21/30) in the control group(P<0.05). Conclusion Heat-sensitive moxibustion combined with medication could increase the blood pressure in both supine and standing position, and decrease the reducing of blood pressure when the position changing from supine to standing in elderly patients with OH of yang-qi deficiency.
[1] Ricci F, De Caterina R, Fedorowski A. Orthostatic hypotension:epidemiology, prognosis, and treatment[J]. J Am Coll Cardiol,2015, 66(7):848-860.
[2] Rose KM, Eigenbrodt ML, Biga RL, et al. Orthostatic hypotension predicts mortality in middle-aged adults:the Atherosclerosis Risk in Communities(ARIC)study[J]. Circulation, 2006, 114(7):630-636.
[3] Kaufmann H. Consensus statement on the definition of orthostatic hypotension, pure autonomic failure and multiple system atrophy[J]. Clin Auton Res, 1996, 6(2):125-126.
[4]翟子琛,向凝.体位性低血压在老年人群中的研究进展[J].中国循证心血管医学杂志, 2021, 13(12):1545-1546.
[5]张逸鑫,孙善斌.督脉温针灸治疗脊髓损伤后体位性低血压临床观察[J].广西中医药大学学报, 2023, 26(2):10-13.
[6]张聪雪.升阳举陷汤治疗老年体位性低血压临床疗效观察[D].北京:北京中医药大学, 2018.
[7]徐利亚,刘如秀,李林光,等.生脉散合四物汤加减治疗老年体位性低血压合并冠心病气虚血瘀证临床研究[J].中国中医药信息杂志, 2023, 30(6):148-152.
[8]陈日新.热敏灸:中医灸法的传承、创新与发展[J].中国针灸,2023, 43(4):483-488.
[9]陈金萍,陈日新,焦琳.陈日新教授悬灸得气经验集粹[J].上海针灸杂志, 2014, 33(9):788-789.
[10]黄仙保,谢丁一,陈日新.陈日新“灸药结合协同增效”学术观点及其在肿瘤康复中的应用[J].中国针灸, 2024, 44(9):1057-1061.
[11] Shibao C, Lipsitz LA, Biaggioni I. ASH position paper:evaluation and treatment of orthostatic hypotension[J]. J Clin Hypertens(Greenwich), 2013, 15(3):147-153.
[12]国家技术监督局.中医临床诊疗术语证候部分:GB/T16751.2–1997[S].北京:中国标准出版社, 2004.
[13]吴勉华,王新月.中医内科学[M]. 3版.北京:中国中医药出版社, 2012.
[14]郑筱萸.中药新药临床研究指导原则(试行)[M].北京:中国医药科技出版社, 2002.
[15]张佳,张茜宇.重视老年体位性低血压和餐后低血压[J].保健医苑, 2023(7):48-49.
[16]郭长在,王少松,夏秋玉,等.督脉火针为主治疗老年神经源性体位性低血压1例[J].中医杂志, 2023, 64(17):1833-1836.
[17]静馨,郭伟聪,陈泽煌.四味回阳饮加味治疗气厥型神经源性体位性低血压30例[J].福建中医药, 2017, 48(6):10-11, 23.
[18]欧阳希林,焦琳,高晓燕,等.陈日新热敏灸动态观的临床验证与体会[J].中医杂志, 2018, 59(12):1006-1010.
[19]郑敏,蒋帅,甘蕾蕾,等.热敏灸联合穴位贴敷治疗后循环缺血性眩晕临床观察[J].山东中医杂志, 2024, 43(5):520-524.
[20]刘军兵,何冠,陈蓉,等.热敏灸结合董氏奇穴治疗风痰上扰型后循环缺血性眩晕的疗效观察[J].中西医结合心脑血管病杂志, 2021, 19(15):2638-2641.
[21]武锋.眩晕、头晕、头昏的局部取穴思路与临床体会[J].北京中医药, 2021, 40(9):1005-1007.
基本信息:
DOI:10.13703/j.0255-2930.20240430-0003
中图分类号:R246.1
引用信息:
[1]陈智军,刘梅花,熊俊等.热敏灸联合西药治疗阳气亏虚型老年体位性低血压:随机对照试验[J].中国针灸,2024,44(11):1245-1248+1272.DOI:10.13703/j.0255-2930.20240430-0003.
基金信息:
江西省中医药管理局科技计划项目:2019A263