中国针灸

目的:观察以健脾益肾法组方穴位埋线治疗为主干预2型糖尿病早期肾病的临床疗效。方法:将60例2型糖尿病早期肾病患者随机分为穴位埋线组和常规治疗组,每组30例。常规治疗组给予西医常规治疗,控制血糖、血压和血脂;穴位埋线组在西医常规治疗基础上,选择双侧脾俞、足三里、肾俞、胰俞为主穴予穴位埋线干预,疗程均为3个月。观察两组患者治疗前后尿微量白蛋白排泄率(UAER)、中医症候总积分和监控指标(血糖、糖化血红蛋白、血压、血脂、尿素氮和血肌酐),对比两组疗效。结果:两组患者治疗后UAER、中医症候总积分均较治疗前降低(P<0.001,P<0.01),穴位埋线组降低更明显(P<0.01,P<0.05);穴位埋线组总有效率为76.7%(23/30),优于常规治疗组的63.3%(19/30,P<0.05)。两组治疗后血糖、糖化血红蛋白、血压、血脂均较治疗前明显改善(均P<0.001),尿素氮和血肌酐无明显变化。结论:穴位埋线配合常规西药治疗不仅能减少2型糖尿病早期肾病患者尿微量白蛋白的排泄,而且还能改善中医症候,其疗效优于单纯常规西医治疗。

Objective To observe the therapeutic effect of type Ⅱ early diabetic nephropathies intervened by acupoint thread embedding for strengthening spleen and benefiting kidney.Methods Sixty cases of type Ⅱ early diabetic nephropathies were randomly divided into an acupoint thread embedding group and a routine therapy group,30 cases in each group.In routine therapy group,western medicine routine therapy was applied to control blood sugar,blood pressure and blood lipid.In acupoint thread embedding group,besides the western medicine routine therapy,thread embedding intervention was given at Pishu(BL 20),Zusanli(ST 36),Shenshu(BL 23) and Yishu(Extra) on both sides as main acupints,and the treatment course was 3 months.Urinary micro-albumin excretion(UAER),total score of TCM syndrome and monitor control indices(blood sugar,blood pressure,blood lipid,urea nitrogen and serum creatinine) in both groups were observed before and after treatment,and the therapeutic effects in both groups were compared.Results After treatment,the indices of UAER and total score of TCM syndrome were all reduced(P<0.001,P<0.01);the reduction in acupoint thread embedding group was more obvious(P<0.01,P<0.05);the total effective rate in acupoint thread embedding group was 76.7%(23/30),superior to that of 63.3%(19/30) in routine therapy group(P<0.05).The blood sugar,blood pressure and blood lipid in both groups were remarkably improved(all P<0.001) after treatment;the urea nitrogen and creatinine had no notable variation.Conclusion Acupoint thread embedding combined with western medicine routine therapy can not only reduce the urinary micro-albumin excretion of type Ⅱ early diabetic nephropathies,but also improve the Chinese medicine symptoms and the therapeutic effect is superior to that of simple western medicine routine therapy.